Endocrine Abstracts

Objective: The aim of this study is to determine serum concentrations of adiponectin (ApN), leptin and ghrelin in different stages of anorexia nervosa (AN) and to evaluate their relationships between biochemical, hormonal and anthropometric parameters.Materials and methods: The study is composed of four groups. Group 1: Treatment-naïve patients with a recent diagnosis of AN (n: 19), Group 2: The weight recovered (10% increase in body weight c...

Introduction: We have reported a case of breast carcinoma complicated by diabetes insipidus due to pituitary metastasis.Case: A 47 years old woman had been referred our clinic with the symptoms of polyuria, polydypsia, weight loss, and fatigue. She had a diagnosis of breast carcinoma for six years, underwent radically mastectomy, chemotherapy and radiotherapy, subsequently. Vertebral metastasis was detected and local radiotherapy was performed six months...

Clinical spectrum of phaeochromocytoma syndromes are very heterogeneous. Sometimes life threatening hypertensive attacks may be the presenting symptom or the clinical picture may be subtle that a nonspecific symptom like fatigue can lead to diagnosis. We herein present two phaeochromocytoma cases with distinct clinical features.Case 1: A 20-year-old female patient admitted to emergency department with blurred vision and headache. She experienced headache...

Introduction: In recent years, interferon (IFN) is used in treatment of chronic hepatitis and the studies about the side effects of IFN therapy are increasing.Objective: We aimed to investigate the effects of IFN therapy on glucose metabolism.Materials and methods: Study group was consisted with 30 patients who were diagnosed as chronic hepatitis. Sixteen of 30 were chronic hepatitis B and 14 were chronic hepatitis C. Diagnose was ...

Introduction: We designed a retrospective study to investigate the clinical presentation, laboratory and pathological findings of 14 patients with ACTH-independent macronodular adrenal hyperplasia.Materials and methods: Diagnose of Cushing’ s syndrome was confirmed by biochemical tests, adrenal hyperplasia was confirmed by pathological examination in all patients.Results: No supression was observed in overnight, low and high d...

Introduction: Differentiated thyroid cancer accounts for 1.5% of all pediatric malignancies. Papillary thyroid cancer (PTC) is the most common subtype and is associated with more advanced disease at diagnosis compared to adults. The aim of this study was to identify long-term outcomes of pediatric PTC.Methods: Records of 30 patients with PTC diagnosed in childhood and adolescence and followed up at Istanbul Faculty of Medicine were reviewed retrospective...

Objective: Transgender individuals endure gender dysphoria and incongruence between physical appearance and gender identity. We aimed to investigate effects of gender affirming treatments on sex hormone levels, mental well being and body image quality of life in these individuals. Material and Method: This is a descriptive cross sectional study. Transgender individuals who were transitioned from pediatric to adult care (n: 12) and who were formerly follo...

Introduction: Effective management of the transition from childhood to adulthood in congenital adrenal hyperplasia (CAH) can reduce the problems that may arise in the follow-up during adulthood.Aim: Evaluation of the clinical characteristics and sociodemographic data of CAH patients transferred from the Pediatric Endocrinology Clinic to the Adult department of our hospital and the comparison of the 2 transition models carried out during this period was t...

Introduction: Type 1 diabetes mellitus (T1DM) requires lifelong management, and a well-designed protocol may facilitate transition from child-centered healthcare systems to adult-oriented systems.Aim: We aimed to evaluate sociodemographic data, clinical features and laboratory parameters that may affect the transition period and post-transition process in T1DM patients.Materials and Methods: We retrospectively analyzed 64 patients ...

Objective: Despite treatment, the quality of life in patients with acromegaly remains lower than in the healthy population due to the classical findings and complications related to the disease. Therefore, in the follow-up of acromegaly, evaluation of quality of life along with symptoms and biochemical parameters is recommended. The aim of our study was to evaluate the quality of life, anxiety and depression status of our acromegaly patients and to assess the factors affecting...